Principal Investigator: Xiaoli Nan
Co-Investigators: Cheryl Holt, School of Public Health, UMCP; Min Qi Wang, School of Public Health, UMCP’ Shana Ntiri, School of Medicine, UMB; and Clement Adebamowo, School of Medicine, UMB
Funding Source: National Cancer Institute; $2,212,269 (2018-2023)
Summary: The 2014 President’s Cancer Panel called underuse of HPV vaccines “a serious, but correctable threat to progress against cancer.” The Cancer Moonshot Blue Ribbon Panel, more recently, identified expanding the use of HPV vaccines as a top priority for cancer prevention, especially in medically underserved populations. Effective communication is crucial to widespread adoption of preventive measures against cancer like the HPV vaccines. Built upon recent advances in communication and behavioral sciences, the proposed project seeks to to develop and evaluate a novel, theory-based message framing intervention to accelerate HPV vaccine uptake among African American adolescents. This project aims to 1) develop culturally appropriate messages framed in gains and losses and pretest these messages through community engagement; 2) determine whether/how the effects of message framing (gain vs. loss) on African American parents’ acceptance of the HPV vaccine are moderated by their prior beliefs about HPV and the HPV vaccine; and 3) evaluate the efficacy of a message framing intervention rooted in message targeting principles through a clinic-based randomized trial. Addressing a critical aspect of health disparities disadvantaging the African American community, this research represents a systematic and timely effort to address the national urgency of optimizing communication strategies for promoting HPV vaccination among key stakeholders.